Approximately 1 in 4 people are genetically susceptible to develop CIRS-WDB (Chronic Inflammatory Response Syndrome-Water Damaged Building) following interior exposure to a WDB. This data was extrapolated from the Alleles Frequency database by Dr Shoemaker. There is a direct cause and effect relationship between toxin containing Water Damaged Buildings and CIRS patients who fail to present an antigen response to their immune system with exposure to these same toxins.

The goal of remediation of a WDB is to clean and return the interior of the building to the level of cleanliness required by the CIRS patient to effect a recovery to their pre-CIRS health status. Whether it be a home, office or school the CIRS patient’s fragile health when exposed to a WDB, places much more emphasis on air quality and safe spaces for human habitation.

It is critical that if you employ a professional to test and remediate your WDB that they are knowledgeable of and adhere to an internationally recognised industry standard of the IICRC (Institute of Inspection Cleaning and Restoration) from the 4th Edition 2015 ‘Standard and Reference Guide for Professional Mould Remediation’ , namely -Standard S520. The ANSI/IICRC S520 is a procedural standard and reference guide for the remediation of mould damaged structures and contents.

Indoor Environmental Professionals (IEP’s) have experience in mould investigation and remediation.  Two reputable widely used businesses in Australia are VA Sciences and Eronmore which are both located in Melbourne but consult Nationally.  Both businesses use scientifically based practice, are widely respected and have a clinical knowledge of the illness of CIRS (Chronic Inflammatory Response Syndrome) and can test and remediate your contaminated home, workplace or school.

IEP’s (Indoor Environmental Professionals) are often part of a multidisciplinary team such as Greencap with branches in Australia and New Zealand. Greencap have an extremely handy quick guide to Professional Mould Assessment and Remediation which can be downloaded from a page on their website. Alternatively some people employ a Building Biologist to manage testing and organise remediation of their WDB (Water Damaged home, workplace, vehicle interior or school).

Fungal DNA testing using quantitative surface dust (containing fungal fragments and spores) PCR analysis is used as an indicator of what the air contains from your WDB.  This can be obtained through Mould Lab here in Australia. The most scientifically proven and accurate test to use is an ERMI (which tests for 36 moulds) or an HERTSMI-2 (which tests for the 5 most common indoor moulds).

The project to remediate a WDB is described in several comprehensive steps by the Indoor Environmental Professionals Panel of Surviving Mold Consensus Statement.

Dr Shoemaker recommends a 4-6 week window after remediation is complete prior to doing the repeat ERMI or a HERTSMI-2. This is the most accurate and economically viable way to ensure the safety of a CIRS-WDB interior space.

Dr Shoemaker suggests clinically, when C4a (a marker of inflammation) is below 20,000 and MSH (a neuropeptide regulatory hormone that drops in predisposed people with CIRS) is less than 35 the building ERMI score must be below 2. These laboratory tested blood results indicate a severely ill CIRS sufferer.

However when the CIRS-WDB patient has a C4a exceeding 20,000 and MSH is below 35 (and therefore a more unwell patient) the ERMI needs to be -1 to improve the response to treatment. These laboratory tested blood results indicate a severely ill CIRS sufferer at the furtherest end of the spectrum.

So with remediation of their WDB, to strict standards, perhaps using a mentioned business above, and a rigorous treatment plan using the Shoemaker Treament Protocol,  a patient can return to pre-CIRS health.


This will delay and hinder the patient, sometimes very considerably in their recovery.